I. Basic Information

Jin Shan, Ph.D., Professor, Doctoral Supervisor

Email: jinshan@hubu.edu.cn

Research Fields: Cell Biology, Neurobiology, Genetics

II. Educational Background

2001.09–2004.07,Institute of Hydrobiology, Chinese Academy of Sciences,PHD.

1990.09–1993.07,Department of Biology, Beijing Normal University, MS.1983.09–1987.07,Department of Biology, Henan Normal University, B. Sc.

III. Work Experience

1996.11–Present, School of Life Sciences, Hubei University, Lecturer, Associate Professor, Professor

2005.08–2008.07, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Postdoctoral Research

1987.07–1990.08, Department of Biology, Henan Normal University, Teacher

1994.05–1995.11, Institute of Plant Genetics and Crop Plant Research (IPK, Gatersleben), Germany, Assistant Researcher. Engaged in the research on the regulation of in vitro differentiation of animal embryonic stem cells

IV. Funding

1.National Natural Science Foundation of China (81871121): Research on the mechanism of lifespan regulation by phosphate transporters, January 2019 - December 2022, Project Leader.

2.National Natural Science Foundation of China (31230045): Molecular mechanism of the occurrence of IBGC by the function of type III sodium-dependent phosphate transporter 2 (PiT2). Key Project of the National Natural Science Foundation of China, 2013.01-2017.12, Participant.

3.National Natural Science Foundation of China (31240083): Analyzing the function of the microtubule-severing protein fidgetin using Drosophila as a model system, 2013.01-2013.12, Project Leader.

4.National Natural Science Foundation of China (81070909): Functional analysis of the microtubule-severing protein Katanin 60. Project of the National Natural Science Foundation of China, 2011.01–2013.12. Project Leader.

5.National Natural Science Foundation of China (30871368): Establishment of a Drosophila model of human Kenny-Caffey syndrome and functional analysis of the pathogenic gene dTBCE, 2009.01–2011.12, Project Leader.

6.Natural Science Foundation of Hubei Province (2003ABA117): Establishment of aDrosophila cell response system for Cecropin B inDrosophilaand research on the application of its products, 2003.01–2005.12, Project Leader.

V. Representative Publications

1. Niu X, Mao CX, Wang S, Wang X, Zhang Y, Hu J, Bi R, Liu Z, & Jin S. (2023) ɑ-Tubulin acetylation at lysine 40 regulates dendritic arborization and larval locomotion by promoting microtubule stability inDrosophila. PLoS One 18: e0280573.

2. Jia Y, Jin S , Hu K, Geng L, Han C, Kang R, Pang Y, Ling, E, Tan E, Pan Y, & Liu W, (2021) Gut microbiome modulatesDrosophila aggression through octopamine signaling, Nature Communication. 12: 2698- 2709

3. Mao C, Wen X, Jin S, Zhang YQ. (2017) Increased acetylation of microtubules rescues human tau-induced microtubule defects and neuromuscular junction abnormalities inDrosophila. Disease models & mechanisms. 1245-1252.

4. Ma X, Li X, Yi P, Wang C, Weng J, Zhang L, Zhu X, Jin S, Liu J. (2017) PiT2 regulates neuronal outgrowth through interaction with microtubule-associated protein 1B. Scientific Reports. 7:17850-17862.

5. Mao CX, Xiong Y, Xiong Z, Wang Q, Zhang Y, Jin S. (2014) Microtubule-severing protein katanin regulates neuromuscular junction development and dendritic elaboration in Drosophila. Development. 141, 1064–1074.

6. Xiong Y, Zhao K, Wu J, Jin S, Yong Q. Zhang Y. (2013) HDAC6 mutations rescue human tau–induced microtubule defects in Drosophila. PNAS. 110, 4604–4609.

7. Yao A, Jin S, Li X, Liu Z, Ma X, Tang J, Zhang Y. (2011) Drosophila FMRP regulates microtubule network formation and axonal transport of mitochondria. Human Molecular Genetics. 20, 51–63.

8. Jin S, Pan L, Liu Z, Wang Q, Xu Z, and Yong Q. Zhang Y. (2009) Drosophila tubulin chaperone E functions at neuromuscular synapses and is required for microtubule network formation. Development. 136, 1571–1581.

9. Jin S，Hu G, Qian Y, Zhang L, Zhang J, Qiu G, Zeng Q, Gui J. (2005) Identification of one intron loss and phylogenetic evolution of Dfak gene in the Drosophilae melanogaster species group. Genetica. 125,223–230.