Ying Xiong, PhD

Associate Professor

Email: ying.xiong(AT)hubu.edu.cn

Research Interests

Investigating the molecular basis of neurological disorders through integrated proteomics, behavioral analysis, and brain imaging, with the aim of discovering biomarkers and therapeutic targets.

Education

· PhD in Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 2012

· Bachelor of Science, Wuhan University, Wuhan, 2005

Work Experience

· Associate Professor, College of Life Sciences, Hubei University, Wuhan (2023-Present)

· Visiting Research Scientist, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing (2021-2023)

· Postdoctoral Fellow, Boston Children’s hospital, Harvard Medical School, USA (2016-2020)

· Postdoctoral Fellow, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing (2012-2015)

Research grants

· Wuhan Science and Technology Innovation Bureau (Wuhan, CN), Grant No. 2024020702030125

· Hubei Provincial Natural Science Foundation, Cultivation Projects of the Innovation Development Joint Fund

Publications

1. Huilin Hong, Chao Guo, Xueru Liu, Liguang Yang, Wei Ren, Hui Zhao, Yuan Li, Zhongyin Zhou, Sin Man Lam, Jidong Mi, Zhentao Zuo, Cirong Liu, Guo-Dong Wang, Yan Zhuo, Ya ping Zhang, Yixue Li, Guanghou Shui, Yong Q. Zhang*, Ying Xiong*. Differential effects of social isolation on oligodendrocyte development in different brain regions: insights from a canine model. Front Cell Neurosci. 2023, 17:1201295

2. Huilin Hong, Zhiguang Zhao, Xiahe Huang, Chao Guo, Hui Zhao, Guo-Dong Wang, Ya PingZhang, Jian-Ping Zhao, Jianhui Shi, Qing-Feng Wu, Yong-Hui Jiang, Yingchun Wang, Lei M Li, ZhuoDu, Yong Q Zhang*, Ying Xiong*. Comparative Proteome and Cis-Regulatory Element Analysis RevealsSpecific Molecular Pathways Conserved in Dog and Human Brains. Molecular & Cellular Proteomics. 2022, 21(8):100261

3. Ying Xiong, Huilin Hong, Cirong, Liu, Yong Q. Zhang. Social isolation and the brain: effects and mechanisms. Molecular Psychiatry. 2022, 28:191-201.

4. Guoli Zhao, Yingga Wu, Li Du, Whenua Li, Ying Xiong, Aiyu Yao, Qifu Wang, Yong Q. Zhang. Drosophila S6 kinase like inhibits neuromuscular junction growth by downregulating the BMPreceptor Thickveins. Plos Genetics. 2015, 11(3): e1004984

5. Chuan-Xi Mao, Ying Xiong, Zhaohuan Xiong, Qifu Wang, Yong Q. Zhang, Shan Jin. Microtubule-severing protein Katanin regulates neuromuscular junction development and dendriticelaboration in Drosophila. Development. 2014, 141(5): 1064-1074

6. Ying Xiong, Kai Zhao, Jiaxi Wu, Zhiheng Xu, Shan J, Yong Q. Zhang. HDAC6 mutationsrescue human tau-induced microtubule defects in Drosophila. Proceedings of the National Academyof Sciences. 2013, 110(12): 4604-9

7. Haiying Zhang, Ling Tian, Stephen Tobe, Ying Xiong, Songyan Wang, Xinda Lin, Yanan Liu, William Bendena, Sheng Li, and Yong Q. Zhang. Drosophila CG10527 mutants are resistant to juvenile hormone and its analog methoprene. Biochemical and Biophysical Research Communications, 2010, 401: 182-187